PD Dr. Carsten Schultz

PD Dr. Carsten Schultz

European Molecular Biology Laboratory (EMBL)
Cell Biology & Biophysics Unit
Meyerhofstr. 1
69117 Heidelberg
Phone: +49 (6221) 387-210
Fax: +49 (6221) 387-518
E-mail: schultz@embl.de


Research Area

Chemical Biology, Organic Chemistry, Cell Biology


Position and Status

Group Leader and Senior Scientist


Scholarships and awards

2013               Metropolregion RN Innovation Price (jointly with E. Lemke)
2012               Heidelberg Molecular Life Science Award (jointly with M. Brunner)
1993 - 1996    Habilitation Fellowship of the Deutsche Forschungsgemeinschaft



Academic Education

09/1986 - 06/1989   Ph.D. work at Fachbereich Biologie/Chemie, University of Bremen, supervised by Prof. Dr. Bernd Jastorff
10/1979 - 08/1986   Study of Chemistry at University of Bremen

 

University Degrees

1997   Habilitation: Organic Chemistry, University of Bremen, Mentor: Prof. Dr. B. Jastorff
1989   Ph.D. degree in Chemistry, University of Bremen, supervised by Prof. Dr. Bernd Jastorff

 

Employment

03/2015 -                 Associate Editor Chemical Science, Royal Society for Chemistry, Cambridge, UK
07/2008 -                 Senior Scientist, EMBL Heidelberg
10/2001 -                 Group leader at EMBL Heidelberg
04/2000 - 09/2001   Group leader at Max-Planck-Institute for Molecular Physiology in Dortmund (Dept. Prof. Dr. H. Waldmann)
05/1996 - 03/2000   Researcher at Fachbereich Biologie/Chemie, Universität Bremen (Prof. Dr. B. Jastorff)
05/1993 - 04/1996   Habilitation Fellow at Fachbereich Biologie/Chemie, Universität Bremen (Mentor Prof. Dr. B. Jastorff)
10/1992 - 04/1993   Research Project Assistant with Prof. Dr. Roger Y. Tsien at the Dept. of Pharmacology, University of California, San Diego
02/1990 - 09/1992   Postdoctoral Fellow with Prof. Dr. Roger Y. Tsien at the Dept. of Pharmacology, University of California, San Diego
07/1989 - 01/1990   Researcher at Fachbereich Biologie/Chemie, Universität Bremen
09/1986 - 06/1989   Doctoral Fellow with Prof. Dr. Bernd Jastorff at Fachbereich Biologie/Chemie, Universität Bremen

Editorial Board Member:

  1. ChemBioChem
  2. ACS Chemical Biology
  3. Chemistry & Biology
  4. Current Methods in Chemical Biology
  5. Chemical Science (Assoc. Editor)
  1. Höglinger, D., Haberkant, P., Aguilera-Romero, A., Riezman, H., Porter, F. D., Galione, A., Platt, F. M., Schultz, C. (2016) Sphingosine releases calcium from lysosomes. eLife, 4. pii: e10616. doi: 10.7554/eLife.10616. [Epub ahead of print].
  2. Ketel, K., Kraus, M., Nicot, A.-S., Puchkov, D., Wieffer, M., Mueller, R., Schultz, C., Laporte, J., Haucke, V. (2016) A phosphoinositide conversion mechanism for exit from endosomes. Nature, in press.
  3. Nadler, A., Yushchenko, D., Müller, R., Stein, F., Feng, S., Carta, M., Mulle, C., Schultz, C. (2015) Exclusive photorelease of signalling lipids at the plasma membrane. Nat. Commun., 6:10056. doi: 10.1038/ncomms10056.
  4. Hu, H.-Y., Vats, D., Vizovisek, M., Kramer, L., Germanier, C., Wendt, K. U., Rudin, M., Turk, B., Plettenburg, O., Schultz, C. (2014) In vivo imaging of mouse tumors by a lipidated cathepsin S substrate. Angew. Chem. Int. Ed. 53:7669-7673.
  5. Feng, S., Laketa, L., Stein, F., Rutkowska, A., MacNamara, A., Depner, S., Klingmueller, U., SaezRodriguez, J., Schultz, C. (2014) A rapidly reversible chemical dimerizer system to study lipid signalling in living cells. Angew. Chem. Int. Ed. 53:6720–6723.
  6. Laketa, V.,Zarbakhsh, S., Traynor-Kaplan, A., MacNamara, A., Subramanian, D., Putyrski, M., Mueller, R., Nadler, A., Mentel, M., Saez-Rodriguez, J., Pepperkok, R., Schultz, C. (2014) PIP3 induces the recycling of receptor tyrosine kinase. Sci. Signal. 7, ra5.
  7. Haberkant, P., Raijmakers R., Wildwater, M., Sachsenheimer, T.,Brügger, B.,Maeda, K.,Houweling, M., Gavin, A.-C., Schultz, C., van Meer, G., Heck, A. J. R., Holthuis, J. C. M. (2013) In vivo profiling and visualization of cellular protein-lipid interactions using bifunctional fatty acids. Angew. Chem. Int. Ed. 52:4033-4038.
  8. Posor, Y., Eichhorn-Gruenig, M., Puchkov, D., Schöneberg, J., Ullrich, A., Lampe, A., Müller, R., Zarbakhsh, S., Schultz, C., Schmoranzer, J., Noé, F., Haucke, V. (2013) Spatiotemporal control of endocytosis by phosphatidylinositol 3,4-bisphosphate. Nature 499:233-237.
  9. Nadler, A., Reither, G., Feng, S., Stein, F., Reither, S., Schultz, C. (2013) The fatty acid composition of diacylglycerols determines local signaling patterns. Angew. Chem. Int. Ed. 52:6330-6334.
  10. Subramanian, D., Laketa, V., Müller, R., Tischer, C., Zarbakhsh, S., Pepperkok, R., Schultz, C. (2010) Activation of membrane-permeant caged PtdIns(3)P induces endosomal fusion in cells. Nat. Chem. Biol. 6:324-326.