Prof. Dr. Francesca Bottanelli

Francesca Bottanelli

Freie Universität Berlin
Institut für Chemie und Biochemie
Thielallee 63
14195 Berlin, Germany
E-Mail: Francesca.Bottanelli@fu-berlin.de
Phone: +49 (30) 838 65860


Research Area

Cell Biology, super-resolution imaging


Position and Status

Junior Professor of Biochemistry (W1)


Scholarships and awards

2012-2014  American-Italian Cancer Foundation post-doctoral fellowship  
2006-2010  Leeds university international research PhD scholarship  



University training and degree

2006 - MSc in Plant, Food and Environmental Biotechnology, University of Milan (IT)
10/2004 - 09/2005 - MSc thesis work at the University of Leeds (UK). Supervisor: Dr. J. Denecke.
01/2004 – 04/2004 - BSc thesis work at the University of Milan (IT). Supervisor: Dr. Gabriella Consonni.

 

Advanced academic qualifications

2011 - PhD in Biology, Faculty of Biological Sciences, The University of Leeds (UK). Supervisor: Dr. J. Denecke.

 

Postgraduate professional career

09/2018 - present - Junior professor, Freie Universitä Berlin, Institut für Chemie und Biochemie, Biochemie.  
04/2011 - 06/2018 - Post-doctoral fellow, Yale University School of Medicine. Cell Biology department (USA). Advisor: Dr. J. Rothman.

Coordinating functions and editorial work

2019 - Present - Member of the executive committee for SFB958 “Scaffolding of Membranes - Molecular Mechanisms and Cellular Functions“.

Most important publications 

  1. Wong-Dilworth, L., Rodilla-Ramirez, C., Fox, E., Restel, S. D., Stockhammer, A., Adarska, P. & Bottanelli, F. STED imaging of endogenously tagged ARF GTPases reveals their distinct nanoscale localizations. Journal of Cell Biology 222 (2023). https://doi.org/10.1083/jcb.202205107
  2. Jatzlau, J., Burdzinski, W., Trumpp, M., Obendorf, L., Roßmann, K., Ravn, K., Hyvönen, M., Bottanelli, F., Broichhagen, J. & Knaus, P. A versatile Halo- and SNAP-tagged BMP/TGFβ receptor library for quantification of cell surface ligand binding. Communications Biology 6, 34 (2023). https://doi.org/10.1038/s42003-022-04388-4
  3. Adarska, P., Wong-Dilworth, L. & Bottanelli, F. ARF GTPases and Their Ubiquitous Role in Intracellular Trafficking Beyond the Golgi. Frontiers in Cell and Developmental Biology 9 (2021). https://doi.org/10.3389/fcell.2021.679046
  4. Hao, X., Allgeyer, E. S., Lee, D.-R., Antonello, J., Watters, K., Gerdes, J. A., Schroeder, L. K., Bottanelli, F., Zhao, J., Kidd, P., Lessard, M. D., Rothman, J. E., Cooley, L., Biederer, T., Booth, M. J. & Bewersdorf, J. Three-dimensional adaptive optical nanoscopy for thick specimen imaging at sub-50-nm resolution. Nature Methods 18, 688-693 (2021). https://doi.org/10.1038/s41592-021-01149-9
  5. Stockhammer, A. & Bottanelli, F. Appreciating the small things in life: STED microscopy in living cells. Journal of Physics D: Applied Physics 54, 033001 (2021). https://doi.org/10.1088/1361-6463/abac81
  6. Bottanelli, F. & Schroeder, L. in Clathrin-Mediated Endocytosis: Methods and Protocols (ed Laura E. Swan) 189-195 (Springer New York, 2018). doi: 10.4081/ejh.2019.3072
  7. Bottanelli, F., Kilian, N., Ernst, A. M., Rivera-Molina, F., Schroeder, L. K., Kromann, E. B., Lessard, M. D., Erdmann, R. S., Schepartz, A., Baddeley, D., Bewersdorf, J., Toomre, D. & Rothman, J. E. A novel physiological role for ARF1 in the formation of bidirectional tubules from the Golgi. Molecular Biology of the Cell 28, 1676-1687 (2017). https://doi.org/10.1091/mbc.e16-12-0863
  8. Bottanelli, F., Kromann, E. B., Allgeyer, E. S., Erdmann, R. S., Wood Baguley, S., Sirinakis, G., Schepartz, A., Baddeley, D., Toomre, D. K., Rothman, J. E. & Bewersdorf, J. Two-colour live-cell nanoscale imaging of intracellular targets. Nature Communications 7, 10778 (2016). https://doi.org/10.1038/ncomms10778
  9. Bottanelli, F., Gershlick, D. C. & Denecke, J. Evidence for Sequential Action of Rab5 and Rab7 GTPases in Prevacuolar Organelle Partitioning. Traffic 13, 338-354 (2012). https://doi.org/10.1111/j.1600-0854.2011.01303.x
  10. Bottanelli, F., Foresti, O., Hanton, S. & Denecke, J. Vacuolar Transport in Tobacco Leaf Epidermis Cells Involves a Single Route for Soluble Cargo and Multiple Routes for Membrane Cargo. The Plant Cell 23, 3007-3025 (2011). https://doi.org/10.1105/tpc.111.085480

For a full list of publications:

https://scholar.google.com/citations?hl=en&user=6MbjQGUAAAAJ&view_op=list_works&sortby=pubdate)