Prof. Dr. Volker Haucke

Prof. Dr Volker Haucke

Leibniz Institut für Molekulare Pharmakologie (FMP)
& Freie Universität Berlin
Institut für Pharmazie,
Robert-Rössle-Str. 10
13125 Berlin
Phone: +49 (30) 947 93 100
Fax: +49 (30) 947 93 109
E-mail: haucke@fmp-berlin.de


Research Area

Molecular Cell Biology, Biochemistry, Chemical Biology


Position and Status

Professor of Molecular Pharmacology (S-W3), Director of the Leibniz Institut für Molekulare Pharmakologie (FMP)


Scholarships and awards

2014               Elected Member of the European Molecular Biology Organization (EMBO)
2003               Young Investigator Award (YIP), European Molecular Biology Organization (EMBO)
1998 - 1999    Long-Term Fellowship Award, Human Frontier Science Program
1997 - 1998    Long-Term Fellowship Award, European Molecular Biology Organization
1995               Short-Term Fellowship Award, European Molecular Biology Organization
1994 - 1997    Boehringer Ingelheim Fellow
1993 - 1994    Dr. Carl-Duisberg-Foundation Scholar
1990 - 1994    Scholarship Holder of the Studienstiftung des deutschen Volkes



Academic Education

03/1994 - 04/1997   PhD, Biozentrum, Univ. of Basel (supervisor: Prof. Dr. G. Schatz)
04/1989 - 02/1994   Study of Biochemistry at Freie Universität Berlin & University of Basel

 

University Degrees

2003   Habilitation (venia legendi) in Biochemistry, Georg-August-Universität Göttingen
1997   Ph.D. in Biochemistry, Biozentrum, University of Basel (summa cum laude; supervisor: Prof. Dr. G. Schatz)
1994   Diploma in Biochemistry, Freie Universität Berlin

 

Employment

01/2012 -                 Full Professor of Molecular Pharmacology (S-W3), Freie Universität Berlin & Director of the Leibniz-Institut für Molekulare Pharmakologie; Faculty Member Charité University Medicine Berlin
09/2005 - 12/2011   Full Professor of Biochemistry (W3), FU Berlin, Institute of Chemistry & Biochemistry, Department of Membrane Biochemistry & Charité Universitätsmedizin Berlin
10/2003 - 08/2005   Professor of Biochemistry (C3), FU Berlin, Institute of Chemistry & Biochemistry, Department of Membrane Biochemistry
05/2000 - 09/2003   Head of Independent DFG Junior Research Group, University of Göttingen
04/1997 - 04/2000   Postdoctoral fellow, Yale University & HHMI (w/ Prof. Pietro De Camilli)

01/2012 -       Editorial Board Member, EMBO Reports
2011 -            Founding-Chair (now vice-chair) & Member, SFB 958 "Scaffolding of Membranes"
2008 -            Member, Study Section, "Biochemistry“ of the German Funding Agency (DFG)
2008 - 2010   Chair, SFB 449 "Structure and Function of Membrane Integral Receptors"
2007 -            Member & Principal Investigator, NeuroCure Cluster of Excellence
2007 - 2012   Editorial Board Member, The Journal of Biological Chemistry
2006 -            Member, Faculty of 1000, Neuronal Signaling
2005 -            Editorial Board Member, Biology of the Cell

  1. Ketel, K., Krauss, M., Nicot, A.S., Puchkov, D., Wieffer, M., Müller, R., Subramanian, D., Schultz, C., Laporte, J., Haucke, V. A phosphoinositide conversion mechanism for exit from endosomes. Nature, in press.
  2. Koo, S.Y., Kochlamazashvili, G., Rost, B., Puchkov, D., Gimber, N., Lehmann, M., Tadeus, G., Schmoranzer, J., Rosenmund, C., Haucke, V. , Maritzen, T. (2015) Vesicular synaptobrevin/VAMP2 levels guarded by AP180 control efficient neurotransmission. Neuron, 88: 330-344 ( co-corresponding authors, both from Haucke lab).
  3. Kononenko, NL, Puchkov, D, Classen, GA, Walter, A, Pechstein, A, Sawade, L, Kaempf, N, Trimbuch, T, Lorenz, D, Rosenmund, C, Maritzen, M, Haucke, V (2014) Clathrin/ AP-2 mediate synaptic vesicle reformation from endosome-like vacuoles but are not essential for membrane retrieval at central synapses. Neuron 82: 981-988.
  4. Gimber, N., Tadeus, G., Maritzen, T., Schmoranzer, J., Haucke, V. (2015) Diffusional spread and confinement of newly exocytosed synaptic vesicle proteins. Nature Communications, 6: 8392 [DOI: 10.1038/ncomms9392].
  5. Daumke, O, Roux, A, Haucke, V (2014) BAR domain scaffolds in dynamin-mediated membrane fission. Cell 156: 882-892.
  6. Wilhelm, B.G., Mandad, S., Truckenbrodt, S., Kröhnert, K., Schäfer, C., Rammner, B., Koo, S.J., Claßen, G.A., Krauss, M., Haucke, V., Urlaub, H., Rizzoli, S. O. (2014) Composition of Synaptic Boutons Reveals the Amounts of Vesicle Trafficking Proteins. Science, 344: 1023-1028.
  7. Posor, Y, Eichhorn-Grünig, M, Puchkov, D, Schöneberg, J, Ullrich, A, Lampe, A, Müller, R, Zarbakhsh, S, Gulluni, F, Hirsch, E, Krauss, M, Schultz, C, Noe, F, Haucke, V (2013) Spatiotemporal Control of Endocytosis by Phosphatidylinositol 3,4-Bisphosphate. Nature 499: 233-237.
  8. Wieffer, M, Cibrián Uhalte, E, Posor, Y, Otten, C, Branz, K, Schütz, I, Mössinger, J, Schu, P, Abdelilah-Seyfried, S, Krauß, M, Haucke, V (2013) PI4K2β / AP-1-based TGN-endosomal sorting regulates Wnt signaling. Curr Biol. 23: 2185-90.
  9. von Kleist, L, Stahlschmidt, W, Bulut, H, Gromova, K, Puchkov, D, Robertson, M, MacGregor, KA, Tomilin, N, Pechstein, A, Chau, N, Chircop, M, Sakoff, J, von Kries, J, Saenger, W., Kräusslich, HG, Shupliakov, O, Robinson, PJ, McCluskey, A, Haucke, V (2011) Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition. Cell 146: 471-484.
  10. Faelber, K, Posor, Y, Gao, S, Held, M, Roske, Y, Schulze, D, Haucke, V, Noe, F, Daumke, O (2011) Crystal structure of nucleotide-free dynamin. Nature 477: 556-560.