Prof. Dr. Peter Robin Hiesinger

Peter Robin Hiesinger

Freie Universität Berlin
Insitute for Biology, Division of Neurobiology
Takustr. 6,
14195 Berlin
Phone: +49 30 838 58698

Research Area

Signaling and Secretion in Neurodevelopment and Neurodegeneration

Position and Status

Professor for Neurobiology (W3)

Scholarships and awards

2014               Offered Full Professorship ‘Lehrstuhl Genetik’, Universität Leipzig, Germany
2013               Offered Full Professorship ‘Chair in Physiology’ at the University of Bristol, UK
2008               March of Dimes Basil O'Connor Starter Scholar Award 2008
2007               American Federation for Aging Research Junior Faculty Research Grant Award
2007               Whitehall Foundation Young Investigator Grant Award
2006               Endowed Scholar New Faculty Award, UT Southwestern Medical Center
2000 - 2002    EMBO Long-Term Fellowship
1999               Boehringer Ingelheim Grant for a 3 months research project in Halifax, Canada

Academic Education

11/1997 - 08/2000   Neurobiology, Albert-Ludwigs-University Freiburg, Germany, PhD, Prof. K.-F. Fischbach
10/1992 - 11/1997   Biology, Albert-Ludwigs-University Freiburg, Germany, Diploma, Prof. K.-F. Fischbach


University Degrees

2000   PhD, Neurogenetics, Albert-Ludwigs-University Freiburg, Germany
1997   M.Sc. (Diplom), Neurobiology, Albert-Ludwigs-University Freiburg, Germany
1994   B.Sc. (Vordiplom), Biology, Albert-Ludwig-University of Freiburg, Germany



03/2015 -                 Professor (W3), Lehrstuhl Neurobiologie, Freie Universität Berlin
09/2012 - 02/2015   Associate Professor (tenured), UT Southwestern, Dallas, TX
2006 - 2012             Assistant Professor (tenure-track), UT Southwestern, Dallas, TX
10/2002 - 08/2006   HHMI Research Associate, Baylor College of Medicine, Houston, TX
09/2000 - 09/2002   EMBO Postdoctoral Fellow, Baylor College of Medicine, Houston, TX

  1. Ozel, M.N., Langen, M., Hassan, B.A., and Hiesinger, P.R. (2015) Filopodial Dynamics and Growth Cone Stabilization in Drosophila Visual Circuit Development. eLife e10721.
  2. Langen, M., Agi, E., Altschuler, D., Wu, L., Altschuler, S., Hiesinger, P.R. (2015) The Developmental Rules of Neural Superposition in Drosophila. Cell 162:120-33
  3. Hassan, B.A. and Hiesinger, P.R. (2015) Beyond Molecular Codes: Simple Rules to Wire Complex Brains. Cell 163:285-91.
  4. Wang, D., Epstein, D., Khalaf, O., Srinivasan, S., Williamson, W.R., Fayyazzudin, A., Quiocho, F.A., and Hiesinger, P.R. (2014) Ca /Calmodulin regulates SNARE assembly and spontaneous neurotransmitter release via v-ATPase subunit V0a1. J. Cell Biol. 205:21-31.
  5. Cherry, S., Jin, E.J., Ozel, M.N., Lu, Z., Agi, E., Wang, D., Meinertzhagen, I.A., Chan, C.C., Hiesinger, P.R. (2013) Charcot-Marie-Tooth 2B mutations in rab7 cause dosage-dependent neurodegeneration due to partial loss of function. eLife 2(0):e01064.
  6. Haberman, A.S., Williamson, W.R., Wang, D., Epstein, D., Rina, S., Meinertzhagen, I.A., and Hiesinger, P.R. (2012) The synaptic vesicle SNARE neuronal Synaptobrevin is required for endolysosomal degradation and prevents adult-onset neurodegeneration. J. Cell Biol. 196, 261- 276.
  7. Chan, C.C., Scoggin, S., Wang, D., Cherry, S., Dembo, T., Greenberg, B., Jin, E.J., Kuey, C., Lopez, A., Mehta, S.Q., Perkins, T.J., Brankatschk, M., Rothenfluh, A., Buszczak, M.*, and Hiesinger, P.R.* (2011) Systematic Discovery of Rab GTPases with Synaptic Functions in Drosophila. Curr. Biol. 21:1704-15. *co-corresponding authors
  8. Williamson, W.R., Wang, D., Haberman, A. and Hiesinger, P.R. (2010). A dual function of V0- ATPase a1 provides an endolysosomal degradation mechanism in Drosophila photoreceptors. J. Cell. Biol. 189: 885-99.
  9. Williamson, W.R., Yang, T, Terman, J.R. and Hiesinger, P.R. (2010). Guidance receptor degradation is required for neuronal connectivity in the Drosophila nervous system. PLoS Biol. 8(12):e1000553
  10. Hiesinger, P.R., Fayyazuddin, A., Mehta, S.Q., Rosenmund, T., Schulze, K.L., Zhai, R.G., Verstreken, P., Cao, Y., Zhou, Y., Kunz, J., and Bellen, H.J. (2005). The v-ATPase V 0 subunit is required for a late step in synaptic vesicle exocytosis in Drosophila. Cell 121, 607-620.