Dr. Steeve Boulant

Center for Integrative Infectious Diseases research
Department of Infectious Diseases, Virology
Heidelberg University Clinic
Schaller research group at CellNetworks
German Cancer Research Center (DKFZ)
Im Neuenheimer Feld 344
Room 020
69120 Heidelberg
phone: +49 (0) 6221 56-7858
handy: +49 (0) 1525 46 48 45 9

Research Area

Virology, Immunity, Molecular Cell Biology, Intracellular Trafficking

Position and Status

Junior Group Leader

Scholarships and awards

2011     Postdoctoral fellowship (2011-2012), GlaxoSmithKline, Boston MA, USA
2010     Pilot and Feasibility award program HDDC, Boston MA, USA
2009     Pilot and Feasibility award program HDDC, Boston MA, USA
2007     Poster award, FASEB Lipid Droplets conference, Vermont USA
2006     Postdoctoral fellowship Marie Curie IEF (2006-2008), Glasgow, UK
2006     Best Oral communication, UK Meeting on the Biology and Pathology of HCV
2005     Postdoctoral fellowship (2005-2006), MRC, Glasgow, UK
2005     Travel award, 11th International Meeting on HCV and Related Viruses
2004     Bridging grant, FRM (2004-2005), Lyon, France
2001     EURODOC fellowship, Lyon-Glasgow exchange grant

Academic Education

2001 - 2003     Ph.D. with Dr. Lavergne and Dr. Penin at the Institute of biology and chemistry of proteins, Lyon, France
2000 - 2001     Master degree in Molecular Biology and Biochemistry, University of Lyon, France
1998 - 2000     Bachelor degree in Molecular Biology and Biochemistry, University of Lyon, France


University Degrees

2003     Ph.D. in Molecular Biology and Biochemistry at the Institute of biology and chemistry of proteins, Lyon, France. Mentors: Dr. Lavergne and Dr. Penin



2012 - present   Junior Group Leader CHS Foundation, University Hospital Heidelberg
2008 - 2012       Postdoctoral associate, Harvard Medical School Boston MA, USA
2006 - 2008       Marie Curie Postdoctoral fellow, MRC Virology Unit Glasgow, UK
2005 - 2006       Postdoctoral associate, MRC Virology Unit Glasgow, UK

Coordinating Functions and Editorial Work

2013 -   Chair of the study section “Cell Biology of Viral Infections” of the Society of Virology (GfV)
2010     Co-organizer of live-cell imaging workshop, Harvard Medical School, USA

  1. Odendall C, Dixit E, Stavru F, Bierne H, Franz KM, Durbin AF, Boulant S, Gehrke L, Cossart P, Kagan JC. (2014) Diverse intracellular pathogens activate type III interferon expression from peroxisomes. Nat Immunol. 15(8):717-26.
  2. Blaising J, Lévy PL, Gondeau C, Phelip C, Varbanov M, Teissier E, Ruggiero F, Polyak SJ, Oberlies NH, Ivanovic T, Boulant S*, Pécheur EI* (2013) Silibinin inhibits hepatitis C virus entry into hepatocytes by hindering clathrin-dependent trafficking. Cellular Microbiology 15(11):1866-82
  3. Blaising J, Lévy PL, Polyak SJ, Stanifer M, Boulant S*, Pécheur EI*. (2013) Arbidol inhibits viral entry by interfering with clathrin-dependent trafficking. Antiviral Res.100(1):215-9.
  4. Boulant S*, Stanifer M, Kural C, Cureton DK, Massol R, Nibert ML, Kirchhausen T (2013) Similar uptake but different trafficking and escape routes of reovirus virions and infectious subvirion particles imaged in polarized Madin-Darby canine kidney cells. Mol Biol Cell. 24(8):1196-207.
  5. Ema Cocucci, Francois Aguet, Steeve Boulant and Tom Kirchhausen (2012) The first five seconds in the life of a clathrin coated pit. Cell 150(3):495-507
  6. Kural C, Tacheva-Grigorova SK, Boulant S, Cocucci E, Baust T, Duarte D, Kirchhausen T. (2012) Dynamics of intracellular clathrin/AP1- and clathrin/AP3-containing carriers. Cell Rep. 2(5):1111-9
  7. Steeve Boulant, Comert Kural, Jean-Christophe Zeeh and Tom Kirchhausen (2011) Actin dynamics counteract membrane tension during clathrin-mediated endocytosis. Nat Cell Biol. 13(9):1124-31
  8. Evelyn Dixit, Steeve Boulant, Yijing Zhang, Amy S. Lee, Bennett O.V. Shum, Nir Hacohen, Zhijian J. Chen, Sean P. Whelan, Marc Fransen, Max L. Nibert, Giulio Superti-Furga, Jonathan C. Kagan. (2011) Peroxisomes and mitochondria cooperate to induce antiviral innate immunity. Cell 141(4):668-81
  9. Boulant S, Douglas M, Moody L, Budkowska A, Targett-Adams P and McLauchlan (2008) Hepatitis C virus core protein induces lipid droplet redistribution in a microtubule- and dynein-dependent manner. Traffic 9(8):1268-82
  10. Boulant S, Montserret R, Hope RG, Ratinier M, Targett-Adams P, Lavergne JP, Penin F and McLauchlan J. (2006) Structural determinants that target the hepatitis C virus core protein to lipid droplets. J Biol Chem 281(31):22236-4